Inequality is now a major focus of development institutions and funders, including the World Bank. Health problems, including chronic and infectious diseases and unequal access to affordable quality medical and public health services, contribute to poverty and inequity globally. Health and development are intricately related, with good health as an important ingredient for wealth, and poor health and resulting high medical expenses contributing to poverty and underachievement. Environmental threats to health are a major contribution to ill health globally, especially related to water and air and to changing habitats for vector borne diseases and extreme weather events as climate change advances. There are important inter relationships between global commerce, trade, access to essential medicines, access to high quality nutrition, the environment and health. Substantial donor and government resources are devoted to addressing global health problems in the 21st century. The course examines the history, global architecture and the economic and development determinants and impacts of global health problems. Class Sessions: Relationship between Economic Development and Health; Demographics of Development – Demographic Dividend and Demographic Divide; Health and Trade; Health and Climate Change, Environmental threats to health; Emerging Infectious Diseases; Global Health Actors and Institutions/Architecture.